Zhang jing yue8/11/2023 EPS were not observed in either group, but dizziness and impaired postural sway were observed in 6 patients treated in control group, may be caused by tiapride hydrochloride. Significant improvements BPSD (from 37.9 ± 16.1 to 19.5 ± 15.6, mean ± SD) ( Figure 3) and Barthel index (from 56.4 ± 34.2 to 62.9 ± 35.2) were observed in the YGS group, but not in the control group. In the control group, 11 patients required treatment with tiapride hydrochloride because of deterioration of BPSD. All participants in both groups completed the trial. The frequency of extrapyramidal symptoms (EPS) and other adverse events were recorded. Meanwhile, cognitive function was estimated by the Mini-Mental State Examination (MMSE), and ADL by the Barthel Index were tested at baseline and the end of the treatment. The Neuropsychiatric Inventory (NPI) test for the assessment of BPSD. Participants were randomly assigned to the YGS group (n = 27) or control (drug-free) group (n = 25) and treated for 4 weeks. Mild-to-severe demented patients who had BPSD (18 men and 34 women age 80.3 ± 9.0 years) were investigated. We reported that Yigan San (抑肝散) could improve BPSD without extrapyramidal side effects. Usually major tranquilizers are used, but they cause extrapyramidal side effects. Traditional Chinese medicine for behavioral and psychological symptoms of dementia (BPSD)īehavioral and psychological symptoms of dementia (BPSD) is the serious clinical problem of dementia. How can we treat geriatric syndrome using traditional Chinese Medicine?ģ. Here, we introduce some evidences of TCM for geriatric syndrome and clinical practice guideline from Japan Geriatrics Society. How can we keep jing in TCM kidney? People seeked the ways, from unexpected to some herbal drugs, training methods. That is to say, TCM had geriatric medicine in 2000 years ago. These thoughts were written in the famous ancient medical text book Huan di nei jing (黄帝内経), written in BC 2nd ~ 1st century. This is the reason of aging and geriatric syndrome. When people become old, the jing in TCM kidney decreases, and the function of whole body goes down. Human inherits essence of life (jing, 精) from his/her parents and keeps it all his/her life. Kidney in traditional Chinese medicine (TCM) is very different from Kidney in Western medicine. In ancient China, people considered this phenomenon as Qi (気) deficiency in Kidney organ (shen xu, 腎虚). To be considered a geriatric syndrome, these conditions must interfere with a person’s daily life. Geriatric syndromes are associated with reduced life expectancy. Geriatric syndromes include many symptoms caused by aging, such as dementia, depression, delirium, incontinence, vertigo, falls, spontaneous bone fractures, failure to thrive, and neglect and abuse.
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